Red Wine, Resveratrol and the Gut | What is Resveratrol? | Dr. Marisol, N.D.

Who doesn’t love to have a nice relaxing glass of red wine after a long day? And sure, it’s alcohol, but it’s okay because red wine is good for you, right? Well, my friends, this may be true (in small doses!) because red wine contains the powerful antioxidant, resveratrol.

Resveratrol does many wonderful things for the body, specifically in the gut, which makes it an excellent nutrient for people with digestive conditions.

I wanted to talk about resveratrol because, well hey, everyone loves a good glass of red wine, right? One of the first questions I get from my patients when we talk about doing a cleanse is, “Really?? Do I have to give up red wine??” And the answer is yes, ideally.

Although, I’ve recently discovered a way to prepare it that makes it okay to enjoy on a cleanse, albeit in very minute dosages, for a therapeutic effect. I’ll spill the beans on how exactly to do this later on in this article.

What is Resveratrol?

Resveratrol is a plant compound that acts as a powerful antioxidant in our bodies. It’s not only found in grapes and red wine, but also in smaller amounts in blueberries, tomatoes, peanuts, dark chocolate, and apples.

Resveratrol Concentration in Grapes

The grape is an interesting fruit because the pinot noir grape is the ‘weakest’ grape that grows well in Oregon, Italy, and France (legendary here!) yet it has the highest antioxidant content, specifically resveratrol1. Pinot noir is the healthiest of red wines.

Learn about the benefits of resveratrol for your health with Dr. Marisol ND. Queen of the Thrones®

Pinot Noir

The pinot noir grape is so weak that it actually has to produce a fungus on its skin in order to survive. So the problem with drinking red wine isn’t necessarily alcohol but also the fungus that grows on the skin of the grape. It is a product of fermentation that gets into the body and upsets the microbiome.

It’s these minute doses of bacteria that are on our food, all the time, that we are ingesting every day. This is one of the reasons we don’t want to be eating leftovers all of the time because leftovers have a lot of bacteria that is latent from manufacturing and transporting of different foods.

Concord

The weaker the grape, the stronger the antioxidant. In red wine, it’s pinot noir grapes. In terms of juice, it would be the Concord grape. They actually have one of the highest nutritional profiles but they are incredibly sweet (which means high in sugar).

Grape Diet

Have you ever heard of the old grape diet? Where you basically eat nothing but grapes for three days?

There actually might be something to this. I was reading Genesis recently, the first chapter of the Bible, and in the biblical days, to cleanse they would basically not consume anything for the first 3 days. So you could do a grape juice fast for the first 3 days, along with water and green tea, to clean up the system and also take in a ton of powerful antioxidants.

What Does Resveratrol Do?

Resveratrol can help women lose weight and maintain healthy estrogen levels2 3. Estrogen dominance is a problem that makes you gain weight, and when you gain weight you produce more estrogen.

So it is a vicious cycle of gaining weight and having high estrogen, which causes symptoms like breast tenderness, moodiness, depression, anxiety, you’re basically all over the map. It is not a fun condition to be in and resveratrol can help with that.

Resveratrol in the Gut

So what does it do for the gut?Dr. Marisol ND. teaches you why wine is an excellent source of resveratrol to benefit your gut health.

Flavonoids are very important in keeping the gut mucosal membrane lining healthy4. If you can’t keep the gut mucosal membrane lining healthy, strong and integral, then the problem arises that you have a weak barrier. Your gut is a barrier to the outside food that is coming into the body. It has to be integral.

Maintaining a Healthy Gut Lining

So we need to work on strategies to keep this barrier closed and strong. What closes the barrier most profoundly? Relaxation! That’s right, NO STRESS! When you are stressed, your body is in the sympathetic state and cortisol is pumping. In this state, your gut mucosal membrane lining is weakened, or leaky as they used to call it.

Leaky Gut was a huge term in the 80s and 90s and people still use it – leaky gut syndrome. Now leaky gut is, in a sense, a stressed out person who has holes in their intestines. So their barrier is no longer working, for the engineers out there (😉) They’ve lost the integrity of the barrier, and things that are not supposed to get through, do. Things leak through that are not in the size they should be, and the body can’t recognize them which causes irritation and allergies.

Stool Transit Time

Stool transit time can actually dictate the number of allergies you have. The less that you go, the more allergies you may have5. Isn’t that incredible? Stool transit time can also dictate the form of stool oro to anal (oroanal transit time)6. So there are all these ways that knowing your transit time can tell you different things about your body.

You Are What You Absorb

Now, resveratrol helps with keeping the gut lining integral. It’s actually imperative to it. In supplement formulas, I add in resveratrol all the time and I make sure people are getting it from their diet as well.

What’s even more important is that people are absorbing and digesting things well. We need to optimize the absorption capacity in our guts in order to really reap the health benefits of resveratrol in our food, drink, and supplements.

Discover how to enhance your gut health with Dr. Marisol ND. research on red wine

Food Hygiene

So resveratrol is awesome to get from red wine, although the bacteria and fermentation products make it not so great on a cleanse. So we can do grapes, but we need to wash them well. I’m going to teach you how to wash them to reduce the bacterial load.

Now I don’t want to get into the hygiene hypothesis… the thing is, this isn’t something you need to do long term, just until you establish a healthier barrier and a healthy microbiome. When the microbiome is functioning well it can tolerate more bacterial load. We need to give it a chance to reset itself within the body, which could take 3-6 months, a year, 2 years…

It depends how devastated it is and it depends on how compliant you are.

To Reset Your Gut You Have 2 OptionsLearn how to reset your gut with Dr. Marisol ND. Queen of the Thrones®

  1. You can reset it by a little wee bit at a time which takes a long time,     OR;
  2. You go all in! Change your practice step by step by step for the fast win.

The second option makes more sense to me! I have a big bucket list. I want to travel, why not get things in gear the RIGHT way, but as quickly as possible?

So, in order to reset the environment, we need to clear what is coming in, allowing the body to rebalance in its own natural way and allow it the space to do what it needs to do – that is digest, absorb and eliminate.

My Favourite Health Tool To Reset The Gut

And here comes in my favorite health tool; Queen of the Thrones® Castor Oil Pack™!

Castor Oil Packs are so great for optimizing and supporting change in the gut more rapidly as they focus on the 5 Foundational Functions:

1. Relaxation

Parasympathetic tone, practicing the pause. How do we get more of the relaxed state as opposed to the stressed state? Castor Oil Packs are like the escape button for your nervous system, which is more related to the pack rather than the actual oil. That’s because when the pack sits on the skin it stimulates receptors in the skin of the nervous system.

Whenever you place an object in an area, tactile soft-touch actually is treating that area7. This soft, pleasurable touch also stimulates hormones, like oxytocin – the love and bonding hormone, as well as dopamine8 – the pleasure hormone of the brain. No side effects from castor oil packs, only benefits!

2. Inflammation & AlkalinityQueen of the Thrones® Castor oil Pack is an excellent anti-inflammatory

Castor oil has been shown to be an excellent anti-inflammatory. Wherever there is inflammation there is acidity, so reducing inflammation increase alkalinity. The enzymes of our bodies cannot work without alkalinity. Our enzymes need proper pH to function well, so castor oil packs help to create this environment.

Castor oil has been shown to be as effective as capsaicin without the irritating effect9. I have done studies in my clinic where half of my patients who are on a cleanse wear their pack, and the other half do not. The half who do their castor oil packs lab results post-cleanse were significantly more improved than those who did not.

3. Maintain Glutathione Levels & Support Detox Pathways

There are not many ways to get glutathione, our super important detoxifying compound. You can take glutathione supplements, but they haven’t been shown to be super effective. You can also get it from whey protein, but this is an issue for a lot of people with allergies and sensitivities. A third way to get it is from rooibos tea, green tea or red raspberry leaf tea to improve glutathione in the gut.

Supplementation with N-acetyl cysteine (NAC) and magnesium can help with glutathione levels, however, most of us are already very deficient in magnesium so the body will first use the magnesium for what it needs, before converting it to glutathione. Sometimes it can be dose-limiting too, because of the potential laxative effect of magnesium.

IV and injection is another way of getting glutathione, but this requires going to the clinic every time. Castor Oil Packs help with the recycling of glutathione. There was a study done on rat lenses where they put the lenses in a dish of glutathione solution, and one in a dish of castor oil. The glutathione levels were actually maintained BETTER in the castor oil solution10.Castor oil packs help you to recycle glutathione in your gut

4. Regulation Of Bowels

Transit time is so, so, SO incredibly important. Without a normal transit time, you have problems with your microbiome, allergies, and toxins recirculating in the body. Normal for men is 1.7 days and for women it is, unfortunately, higher at 2.3 days11.

Yes, us women are more complicated! We also have more hormones that play a role in our transit time too. If our progesterone is low, it can contribute to a slower transit time. These are all things that need to be taken into account.

5. Breaking Down Biofilm

Biofilm is basically a sticky coating of glycoproteins and hyaluronic acid, a matrix created by bacteria from their waste products. It’s no different than what surrounds all of the cells of our body. It’s like an extracellular matrix made for bacteria to keep them safe from evil enemies on the outside.

The only problem is that these bacteria are actually the evil enemies to us because they are inoculating a gut that should be healthy. They’re straight up con artists, which is why I call them conbiotics™. You see, bacteria is really good for us and “commensal” bacteria is actually awesome!

Commensal bacteria create vitamins for us, like the ever important B vitamins, as well as L-butyrate and short-chain fatty acids which help to heal the gut lining. It’s amazing what they do for us! But unfortunately, the bad guys can create gas that basically slows our transit time down, like hydrogen disulfide and methane gas12.Queen of the Thrones® Castor Oil Packs™ improve your bowel movements

So it’s super important to address biofilm. There aren’t many natural substances that have the ability to break it down. Castor oil is one of these substances and it’s so amazing because it stimulates nitric oxide passageways!

Nitric oxide is a gasotransmitter, which is basically a gaseous messenger molecule involved in signaling to open up blood vessels and also helps reduce inflammation. They’re calling it one of the newest anti-aging molecules. Red wine, grapes, and beets are all food sources of nitric oxide.

The biggest reason I have people do castor oil packs is that they are such a simple treatment that work on thes 5 foundational functions – relaxation, inflammation, antioxidant status, the bowels, and the microbiome. This supports everything absorbing, digesting, working well, and eliminating where it needs to. To get your own super easy, 3-step Queen of the Thrones® Castor Oil Pack™.

Gut Lining and Hormones

Resveratrol acts like an antioxidant that heal the gut lining

Resveratrol basically acts like an antioxidant that helps heal the gut lining, and at the same time balances out hormones. Our gut lining is very dependant on our hormones, and resveratrol helps in the detoxification of estrogen. When you have better-balanced levels of estrogen, you will have sufficient levels of progesterone that help you go to the bathroom well and maintain a regular transit time.

You go to the bathroom more often when you have higher levels of progesterone. Ladies, right before your period do you find that you are going to the bathroom more frequently? This is because your progesterone levels spike just before menstruation, causing your transit time to speed up.

Dietary Intake of Resveratrol

1. Royal Red

If you’re on any kind of cleansing diet you want to do it the smart way and pasteurize it. Pasteurization, according to Louis Pasteur, was done via a flash-fry method. So basically you boil water, add it to red wine then cool it down immediately. And that’s a great way to get rid of the majority of bacteria and fermentation products that may be in red wine and causing problems for the body.

Try to avoid South America and Californian wines, because they’ve been shown to have high levels of toxicity in them. Organic wines from the European Union-Spain, Italy, France, and Pinot Noir are best. Wines from New Zealand, Australia, Canada, and Oregon are also good options.

How to Flash Pasteurize Red Wine:Follow the advices of Dr. Marisol ND. Queen of the Thrones® about red wine for gut health

You will need:

  • 1 oz red wine
  • 4 oz boiling water
  • Throw in 5 ice cubes

And there you have it, a nice wine cider basically that I like call it the Royal Red! Another option is to add carbonated water and ice for a spritzer type drink.

2. Grape Juice

Grape juice is another option for dietary intake of resveratrol. As mentioned before, Concord grapes have the highest antioxidant content. With grape juice though, water it down because it’s very sweet, therefore very high in sugar!

3. GrapesDiscover with Dr. Marisol ND. how grapes and resveratrol improve your digestive health

Good ‘ole grapes are also a great way to get resveratrol into your system. But remember we talked about the fungus that they produce to protect themselves? We need to wash it off with a handy dandy acid-cleansing wash.

How to make an Acid-Cleansing Wash

You will need:

  • 1 part white vinegar
  • 1/4 part hydrogen peroxide
  • 5 parts water
  • 1 tsp baking soda

Put grapes into a bowl, then add the mixture of liquids and drop in the baking soda. You can also do this with any dried goods like rice, grains, and legumes. It takes off the bacterial load and grapes are super important to do this for.

So the next time you reach for your glass of red wine, I hope you will see it in a whole new light.  Make sure to practice your castor oil pack so you can absorb the awesome benefits of resveratrol, and use these food hygiene tricks to reduce the amount of bacterial load coming into your beautiful temple.

Don’t forget to share this with your friends on social media, through email and to like us on Facebook, Instagram and YouTube to learn more about to joining the movement so that we can all have an improvement!

Disclaimer: Any opinions, advice, statements, services, offers, information or content expressed or made available by third parties, including information providers, are those of the respective authors or distributors. Neither Queen of the Thrones® nor any third-party provider of information guarantees the accuracy, completeness, or usefulness of any content. This communication does not create a doctor-patient relationship. Information provided does not replace the advice of your health care practitioner. If you happen to purchase anything we promote, in this or any of our communications, it’s likely Queen of the Thrones® will receive some kind of affiliate compensation. Still, we only promote content and products that we truly believe in and share with our friends, family and patients. If you ever have a concern with anything we share, please let us know at care@drmarisol.com. We want to make sure we are always serving Our Queendom at the highest level.

References:

1. Lukas Snopek 1 ID , Jiri Mlcek 1,*, Lenka Sochorova 2 , Mojmir Baron 2 , Irena Hlavacova 1 , Tunde Jurikova 3 ID , Rene Kizek 4 , Eva Sedlackova 1 and Jiri Sochor 2. Contribution of Red Wine Consumption to Human Health Protection. Molecules. Received: 15 May 2018; Accepted: 9 July 2018; Published: 11 July 2018 https://pdfs.semanticscholar.org/399f/b972ac0e63c75459c5fb11bf303f4e2677a2.pdf

2. Bagchi D1, Das DKTosaki ABagchi MKothari SC. Benefits of resveratrol in women’s health. Drugs Exp Clin Res. 2001;27(5-6):233-48.

3. Rupali Sharma,1 Neel Kamal Sharma,2 and M. Thungapathra1 Resveratrol regulates body weight in healthy and ovariectomized rats Nutr Metab (Lond). 2017; 14: 30. Published online 2017 Apr 14. doi: 10.1186/s12986-017-0183-5 PMID: 28413432

4. Harald P Hoensch and Reinhard Oertel Emerging role of bioflavonoids in gastroenterology: Especially their effects on intestinal neoplasia World J Gastrointest Oncol. 2011 May 15; 3(5): 71–74. Published online 2011 May 15. doi: 10.4251/wjgo.v3.i5.71 PMID: 21603032

5. Johan Bohlin,1,* Erik Dahlin,1,* Julia Dreja,2 Bodil Roth,1 Olle Ekberg,2 and Bodil Ohlsson1 Longer colonic transit time is associated with laxative and drug use, lifestyle factors, and symptoms of constipation Acta Radiol Open. 2018 Oct; 7(10): 2058460118807232. Published online 2018 Oct 22. doi: 10.1177/2058460118807232 PMID: 30364803

6. Lewis SJ1, Heaton KW. Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol. 1997 Sep;32(9):920-4.

7. Walker SC1, Trotter PD2, Swaney WT2, Marshall A3, Mcglone FP4. C-tactile afferents: Cutaneous mediators of oxytocin release during affiliative tactile interactions? Neuropeptides. 2017 Aug;64:27-38. doi: 10.1016/j.npep.2017.01.001. Epub 2017 Jan 19.

8. Rolls ET et all. Representations of pleasant and painful touch in the human orbitofrontal and cingulate cortices. Cereb Cortex. 2003 Mar;13(3):308-17. ( Dopamine release, Limbic System of brain- Fatty Meal Satisfaction)

9. Vieira C et al. .Effect of ricinoleic acid in acute and subchronic experimental models of inflammation. Mediators Inflamm. 2000;9(5):223-8.

10. Holm TBrøgger-Jensen MRJohnson LKessel L.Glutathione preservation during storage of rat lenses in optisol-GS and castor oil. PLoS One. 2013 Nov 19;8(11):e79620. doi: 10.1371/journal.pone.0079620. eCollection 2013.

11. Johan Bohlin,1,* Erik Dahlin,1,* Julia Dreja,2 Bodil Roth,1 Olle Ekberg,2 and Bodil Ohlsson1 Longer colonic transit time is associated with laxative and drug use, lifestyle factors, and symptoms of constipation Acta Radiol Open. 2018 Oct; 7(10): 2058460118807232. Published online 2018 Oct 22. doi: 10.1177/2058460118807232 PMID: 30364803

12. Suri J1, Kataria R2,1, Malik Z2,1, Parkman HP2,1, Schey R2,1. Elevated methane levels in small intestinal bacterial overgrowth suggests delayed small bowel and colonic transit. Medicine (Baltimore). 2018 May;97(21):e10554. doi: 10.1097/MD.0000000000010554.

Irritable Bowel Syndrome and the Microbiome | Part 2 | Dr. Marisol

Last week in my blog post,  Irritable Bowel Syndrome and the Microbiome | Part 1, we learned about the theories of Pasteur and Bernard, germ theory vs. terrain theory. And, contrary to popular belief in western medicine, it seems that the terrain is the most important aspect when managing the bug.

Probiotic Supplements – Do they Make Sense?

Let me put it in two clear examples for you. You’re told to take probiotics. One pill a day that has 50 billion bacteria. Does it really make sense that this is going to compensate for the 100 trillion bacteria that you have in your intestine? One pill. Wow, must be some kind of magical mystical pill.

What happens when you stop taking it or change your diet or lifestyle? You’re going to have to take way more probiotics if your lifestyle and environment becomes sicker, or way less if your lifestyle and environment becomes healthier. Capiche? Do you see why addressing the body as a whole makes way more sense?

Fecal Transplants – Do they Make Sense?

 What about the big buzz word these days, fecal transplants. They are probably more of a buzz because of their inherent shock factor.

Learn about Irritable Bowel Syndrome IBS with Dr. Marisol ND. Queen of the Thrones®

They make sense for the moment if you’re willing to be a candidate to put someone else’s poo into your body. In lab studies, transplanting an IBS patient’s stools into healthy mice actually gave the mice unhealthy metabolic profiles, different from the healthy stools1.

However, I caution… again, you can transplant the stools, but if your lifestyle and environment, your millieu changes, due to stress or the other factors, what happens is your microbiome will change too. Back to the beginning, no further ahead, only a little bit more full of shit (LOL!).

It’s so simple it hurts my head. I hope it’s hurting yours (not because I want to inflict pain, but I want your eyes to open!)

IBS as a Functional Disorder

In addition to all of this, irritable bowel syndrome is a FUNCTIONAL disturbance of the digestive tract. Does it not then beg for treatment that is functional in form, hence a SYSTEMS biology approach, and not one that reduces it down simply to the microbiome2?

The point of this whole blog is this….

IT’S ABOUT LOOKING AT THE BIG AND THE SMALL, SIMULTANEOUSLY.

Dr. Marisol Teijeiro. Queen of the Thrones® and Medical Mystic

Because this is the natural logic in our living system. Some systems are grand and complex, like our hormonal regulatory system, and others are less complex and small, like a bacterium. But the reality is that because they all exist together, they must all work together.

The issue for Bernard was that his workings appreciated that we lived as a whole of our systems, and that physiological phenomena always seemed to find balance with highly defined set points. So now I’m encouraging you to think of the whole and not the parts in isolation when you’re considering what to do about your irritable bowel.

What would a systems/whole approach entail?

1. Get the Junk Out – Don’t Let It Pile Up

Terrain is, in effect, how we keep our bodies clean from the waste that perturbs its natural function. Think of it like this. If you kept the garbage piling up in your house, instead of packaging it and taking it to the curb, eventually you wouldn’t be able to get into your house to do the things that you need to. The body is no different. Whether the garbage comes from the byproducts of the microbiome, your own metabolism or the food that you eat, at the end of the day it’s all garbage.

Another analogy that I just love is thinking of the fish tank. A fish, in essence, swims in its own filth unless you clean out the tank. Think of the fish like one of your cells. It spits out, pisses and poops out what it doesn’t need into the water. If your body, or the fish tank, is never cleaned, you get scum build up. The scum that makes the glass cloudy and eventually makes it difficult for the fish, a.k.a. the cell, to survive. This is a good way to understand “le millieu liquide” as Bernard understood it.

The focus has shifted from keeping up on housekeeping rather than having a war on the virus. The premise is a strong system that is free of debris. Its “vital force” is intact and it is able to keep the balance between the good and the bad3.

2. Nurture It Like you Would a Garden

I look at it as if our body is a garden. We must feed it, give it water and light, sing to it, make it joyous, reduce the stress, try to avoid natural disasters and natural prey.

As any farmer will tell you, and I have had this conversation with many of my patients that are farmers… “You reap what you sow. If you put in good, you get out good, and more importantly, good takes time.”

We are not looking at dropping a nuke and killing off all the bugs, rather we are willing to put in the time day to day, to get good results. Farmers very much resonate with natural medicine and systems biology because they live it on a daily basis in their work, so it’s so very easy to extend it into their lives.

Our #1 Product to Help with Understanding what our Body is Saying

To help you figure out what the problem is, you fortunately have something very close at your disposable, a totally free assessment. Your stools are one of the best ways to understand what is going on inside your body.

Poop is classically known in our language as #2, but I firmly believe that it was mislabeled and should be called #1, as it is the most important product we produce. It gives us real-time knowledge about what is going on in our bodies. As long as we learn to poop, peek and then assess, we’ve got it all covered.

Our stools are the window into our digestion, absorption, and elimination. They show vitamin and mineral deficiencies, hormonal, immune, and nervous system problems. They suggest inflammation, food sensitivities, excess mucus in the body. They are basically the owner’s manual to your health… If you know how to read them.

Dr. Marisol, Queen of the Thrones® - Digestive Detective

Poo comes in all shapes and forms and sizes, and that is exactly how we like it because that’s how it is used as a guide to your body’s health. Whether it’s a cow plop or an Oktoberfest sausage… whether it sinks or floats… whether or not it smells like rotten eggs… They’re all key indications to the state of our health.

Start your gut health journey now and grab your complimentary check list to find out what the colour of your poo says about you in my gut health guide; 50 Shades of Poo!

Environments Have Timing, So Does your Poo

Another majorly important factor is timing. All systems have timing. With your stools, it’s incredibly important for them to work well and for you to track how often and when you go. The ideal is a 24-hour cycle. A longer stool timing is linked to increased allergy and food sensitivity4, as one example, but there is much more it is linked to.

Timing is everything. Even your microbiome is doing different things depending on the clues in your environment5, following the day and night cycle, or circadian rhythm. So it makes sense that when you’re working on your systems, or your terrain, to start with the most important cycle to optimize.

Change your Terrain – Fix your Irritable Bowel

So now, what are you thinking? Do you still want to target the microbiome? I doubt it! I think now you understand that you must fix the environment and the rest will follow (there are a few exceptions to this rule, so always make sure that you check with your health care provider for what is right for you).

Night Practice for Irritable Bowel Terrain Treatment

My most important medicines for the terrain are the oldest therapies of them all. Likely because they had their roots long ago when people were in tune with these vitalistic principles.

Nightly Restorative Sleep Practice

Sleep is the most important part of our day. So like I do with all of my patients, we start here. We do the majority of our house-work while we’re sleeping, unbeknownst to you… As long as you get a deep and regenerative sleep. Even the microbiome potentially follows the natural day and night cycles6!

Queen of the Thrones® Castor Oil Pack™ help you to cope with Irritable Bowel Syndrome IBS

If you were like me, when I was in the stormy season of my irritable bowel, I couldn’t sleep for the life of me. Because of this, I was a mess emotionally and my WHOLE life felt like a mess, a hot mess. One of the top complaints made by irritable bowel syndrome sufferers is fatigue. And this is no surprise because if your body is confused with its hormones, nutrient deficiencies and microbiome mayhem, how can you get a good night sleep?

 

These are the most important tips:

  • Cool your room
  • Complete darkness
  • Your bed is for sex and sleep only – try having sex before sleep that’ll help you doze off into never, never land
  • Don’t eat for at least 2 hours before bed
  • Avoid caffeinated beverages past 3 pm (coffee, tea, green tea, pop, energy drinks)
  • Alcohol – don’t over do it, it’ll wake you
  • Create a routine every night, the same thing
  • Journal for one page, write down what you need to do tomorrow and 3 things that you are grateful for
  • Wear an eye mask like the one in the Beauty Sleep Brow & Lash Kit™ – this helps to naturally promote melatonin7 which does wonders for your sleep!
  • Use your castor oil pack!

Castor Oil Packs – A Legendary Terrain Treatment

Castor Oil Packs deserve special mention. So many of us go to bed stressed out and worried about the next day. So we tumble, toss and turn, and do nothing but hyper worry about the day we just had and what’s to come.

When you place a castor oil pack on your body it immediately switches your system into the relaxed state. Ah, zen time for me. So you can sleep and heal and reap the benefits. Get your Queen of the Thrones® Castor Oil Pack Pack™ and 500ml Castor Oil Bundle!

Queen of the Thrones® Beauty Sleep Brow & Lash Kit™ helps you sleep better

On top of it, there are so many wonderful actions of the pack that help your body to do the clean up during the night. They help to:

  1. Reduce inflammation and improve the alkalinity of your body8 9
  2. Enhance antioxidants like glutathione that help your body to cleanse10
  3. Move the bowels – typically the next morning you’re happy to let go of a load!11 12
  4. Breakdown biofilm – a barrier created by the bad bugs of the microbiome. Getting rid of this gunk allows you to heal your gut 13 14
  5. Don’t forget they help you to relax15 16 so you can sleep!

Your sleep will be regenerative, healthy, fulfilling, and satisfying. You’ll be ready to take on your day. Most importantly, you will have done the important step of helping to reset your terrain while you sleep.

NEXT STEPS

My hope is that you start by looking at what your poo is saying about you and that you begin to address the ever-important sleep function of your body. I love the saying, “cleanliness is next to godliness”, and starting these practices are the very first steps to getting your body in a better, healthier, and cleaner state. 

Don’t forget to share this with your friends on social media, through email and to like us on Facebook, Instagram and YouTube to learn more about joining the movement so that we can all have an improvement!

Disclaimer: Any opinions, advice, statements, services, offers, information or content expressed or made available by third parties, including information providers, are those of the respective authors or distributors. Neither Queen of the Thrones® nor any third-party provider of information guarantees the accuracy, completeness, or usefulness of any content. This communication does not create a doctor-patient relationship. Information provided does not replace the advice of your health care practitioner. If you happen to purchase anything we promote, in this or any of our communications, it’s likely Queen of the Thrones® will receive some kind of affiliate compensation. Still, we only promote content and products that we truly believe in and share with our friends, family and patients. If you ever have a concern with anything we share, please let us know at care@drmarisol.com. We want to make sure we are always serving Our Queendom at the highest level.

References:

1 De Palma G1, Lynch MD2, Lu J1, Dang VT3, Deng Y1, Jury J1, Umeh G1, Miranda PM1, Pigrau Pastor M1, Sidani S1, Pinto-Sanchez MI1, Philip V1, McLean PG4, Hagelsieb MG5, Surette MG1, Bergonzelli GE4, Verdu EF1, Britz-McKibbin P3, Neufeld JD2, Collins SM1, Bercik P6. Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice. Sci Transl Med. 2017 Mar 1;9(379). pii: eaaf6397. doi: 10.1126/scitranslmed.aaf6397.

2 Şimşek I1. Irritable bowel syndrome and other functional gastrointestinal disorders. J Clin Gastroenterol. 2011 Aug;45 Suppl:S86-8. doi: 10.1097/MCG.0b013e31821fbd6f.

3 Normandin S1. Claude Bernard and an introduction to the study of experimental medicine: “physical vitalism,” dialectic, and epistemology.  J Hist Med Allied Sci. 2007 Oct;62(4):495-528. Epub 2007 Jun 18.

4 Pali-Schöll I1,2, Untersmayr E3, Klems M4, Jensen-Jarolim E5,6. The Effect of Digestion and Digestibility on Allergenicity of Food. Nutrients. 2018 Aug 21;10(9). pii: E1129. doi: 10.3390/nu10091129.

5 Nobs SP1, Tuganbaev T1, Elinav E2,3. Microbiome diurnal rhythmicity and its impact on host physiology and disease risk.EMBO Rep. 2019 Mar 15. pii: e47129. doi: 10.15252/embr.201847129. [Epub ahead of print]

6 Liang X1, FitzGerald GA2. Timing the Microbes: The Circadian Rhythm of the Gut Microbiome. J Biol Rhythms. 2017 Dec;32(6):505-515. doi: 10.1177/0748730417729066. Epub 2017 Sep 1.

7 Hu RF1, Jiang XY, Chen J, Zeng Z, Chen XY, Li Y, Huining X, Evans DJ. Non-pharmacological interventions for sleep promotion in the intensive care unit. Cochrane Database Syst Rev. 2015 Oct 6;(10):CD008808. doi: 10.1002/14651858.CD008808.pub2.

8 Vieira C et al. .Effect of ricinoleic acid in acute and subchronic experimental models of inflammation. Mediators Inflamm. 2000;9(5):223-8.

9  Grady H. Immunomodulation through castor oil packs. The Journal of Naturopathic Medicine. Volume 7 Jan 1 1998; 7(1): 84-9

10  Holm T1, Brøgger-Jensen MR, Johnson L, Kessel L. Glutathione preservation during storage of rat lenses in optisol-GS and castor oil. PLoS One. 2013 Nov 19;8(11):e79620. doi: 10.1371/journal.pone.0079620. eCollection 2013.

11  Arslan GG, Eşer I. An examination of the effect of castor oil packs on constipation in the elderly. Complement Ther Clin Pract. 2011 Feb;17(1):58-62. doi: 10.1016/j.ctcp.2010.04.004. Epub 2010 May 18.

12  Sorin Tunaru,a Till F. Althoff,a Rolf M. Nüsing,b Martin Diener,c and Stefan Offermannsa,d,1 Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptorsProc Natl Acad Sci U S A. 2012 Jun 5; 109(23): 9179–9184.Published online 2012 May 21. doi: 10.1073/pnas.1201627109PMID: 22615395

13  Andrade IM1, Andrade KM2, Pisani MX1, Silva-Lovato CH1, de Souza RF1, Paranhos Hde F1. Trial of an experimental castor oil solution for cleaning dentures. Braz Dent J. 2014 Jan-Feb;25(1):43-7.

14  Badaró MM, Salles MM, Leite VMF, Arruda CNF, Oliveira VC, Nascimento CD, Souza RF, Paranhos HFO, Silva-Lovato CH. Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser.J Appl Oral Sci. 2017 May-Jun; 25(3):324-334.

15  Walker SC1, Trotter PD2, Swaney WT2, Marshall A3, Mcglone FP4. C-tactile afferents: Cutaneous mediators of oxytocin release during affiliative tactile interactions? Neuropeptides. 2017 Aug;64:27-38. doi: 10.1016/j.npep.2017.01.001. Epub 2017 Jan 19.

16  Rolls ET et all. Representations of pleasant and painful touch in the human orbitofrontal and cingulate cortices. Cereb Cortex. 2003 Mar;13(3):308-17. ( Dopamine release, Limbic System of brain- Fatty Meal Satisfaction)

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Best Lab Tests to Help Treat Your Irritable Bowel Syndrome

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So you’ve been diagnosed with irritable bowel syndrome (IBS). Now what?? As someone who has IBS, I’ve experienced first hand how debilitating it can be, and how confusing the diagnostic process is. I want to share with you some things that I wish I would have known back when I got my diagnosis, that would have saved me years of excruciating pain and suffering. I have now seen thousands of patients who also have this diagnosis live a legendary life.

Why is Irritable Bowel Syndrome a Functional Bowel Movement Disorder?

Irritable bowel syndrome is classified as a chronic functional bowel movement disorder because it is diagnosed by the symptoms that you are experiencing. These are typically abdominal pain, gas, bloating, and changes in bowel movements, often diarrhea or constipation1. Other digestive diseases that can be seen by colonoscopy or confirmed by lab tests are often excluded before IBS is diagnosed.

Why Can’t Labs Tell Me That I Have Irritable Bowel Syndrome?

The labs that most conventional doctors use at this moment in time don’t give a definitive diagnosis of irritable bowel syndrome. This is because it is a complex interplay of all the processes in our body. It is most often a reaction to stress in the body, whether emotional or physical, that creates an imbalance in the immune, nervous and hormonal systems. This compounds and affects the natural digestive processes of the gut, causing inflammation, irritation, dysbiosis and lack of digestive factors that all contribute to and aggravate our symptoms2.

The big point here is that it is NOT just one thing causing IBS, and to treat it you need to have a MULTIFACTORIAL approach or it just won’t work.

Functional Disorders Involve the ENTIRE Environment of the Body 

As a Naturopathic Doctor, we look at the body as a complete environment, an ecosystem. I have expertise in digestive disorders, specifically irritable bowel syndrome. I am also extremely well versed in hormonal problems such as hypothyroid, estrogen dominance, nervous system conditions like anxiety and depression, and immune system problems like Hashimoto’s thyroiditis, celiac disease, cancer, Crohn’s, ulcerative colitis and I have treated all successfully.

If I only knew about the gut and digestive system, I wouldn’t be able to treat a FUNCTIONAL digestive system disorder because functional means that the whole entire body is involved. The ecosystem needs rebalancing.

Are There Functional Tests for Irritable Bowel Syndrome?

Yes, there are things that can be tested, but again, it is a whole body approach. So as a Naturopathic Doctor I can see that there are imbalances in the whole body.

What Is the Point of Testing in Irritable Bowel Syndrome?

First off, it’s important to do tests to rule out other conditions. When the diagnosis is clear, I test irritable bowel patients in order to track improvements and direct and guide treatment.

For my health as well, I have noticed that it is vital to have this tracking system over time in order to gain a good understanding of what is going on inside your system, year to year.

Since irritable bowel is a chronic, long term disease, being proactive in this way helps to stay on top of things and avoid the frustration and suffering of living with uncomfortable symptoms.

Stress Hormone Testing Cortisol and ACTH 

Research demonstrates that people with irritable bowel syndrome, mainly women, with onset at a younger age3, will have it for the greater part of their lives. They typically also have an imbalance in their nervous system and stress response.

Lab tests help to treat your Irritable Bowel Syndrome

Stress markers of cortisol in the blood can be tested and show a difference between men and women as well as between healthy and unhealthy subjects4. However, this is a costly test and is not common protocol for irritable bowel syndrome.

Salivary or urine cortisol markers can also be used to measure this, and they are my markers of choice. Research demonstrates that there is a significant difference in cortisol (stress hormone) markers in the morning and evening, and in general there was a higher spike in the a.m. and lower in the evening. The pattern of circadian rhythm night and day curve was still maintained5.

These tests can be purchased on YourLabWork.com.

Sleep is often something that is a complaint for women with IBS and there seems to be a difference between the type, whether it be IBS-D (diarrhea predominant) or IBS-C (constipation predominant)6. Sleep is something that normally balances our regulatory systems as it helps to reset the immune, nervous and hormonal systems.

I recommend wearing an eye mask to bed at night to help support natural melatonin production, without having to take a supplement. I’ve created the Beauty Sleep Brow & Lash Kit that uses Castor Oil applied around the eyes, eyelashes and eyebrows, covered by a sleep mask. This has a relaxing effect on the system and improves natural melatonin levels, helping you to get a good night’s sleep. You will note over time, visible differences in sleep quality with using a mask7. Get your own Queen of the Thrones® Beauty Sleep Brow & Lash Kit™ and improve your sleep.

Inflammation Testing in IBS 

Inflammation is a key component in IBS. Inflammation may be sourced from food sensitivities, allergies and intolerances, or choices of food, such as fermented foods that have high levels of histamine and act as an irritant to the gut. Inflammation is a root cause of all diseases and when there is imbalance in any system there is always inflammation.

Ferritin, the storage molecule for iron can also be a key indicator of acute inflammation. It is important to test in combination with a complete blood count (CBC) as well as an iron panel to make sure you rule out any other reasons for an elevated level of Ferritin.

In my practice there are certain key markers that I have noted are indicative inflammation. Firstly, high sensitivity C reactive protein (HS-CRP). This marker is not often tested, however, levels have been noted to be higher in those with irritable bowel syndrome as compared to the healthy population8.

Cholesterol has also been one of the markers of inflammation that I use to track progress in patients. It is linked to inflammatory processes in the body and I have seen clear indications post therapeutic cleansing interventions with my patients, where even if cholesterol is only moderately higher, it always decreases from the pre-testing phase9. I always test these levels in my IBS patients because I want to see how they are adapting to their protocols and where they are at the present state in time.

A complete blood count (CBC) is always important to do as well, because it demonstrates a variety of markers. With regards to inflammation, eosinophils are a marker of allergy and when they are elevated it’s an indicator that there is elevated histamines in the body10. It’s most commonly correlated to parasite infection, which is something to be considered in irritable bowel syndrome, since the onset of IBS can be due to a gastrointestinal infection11.

In my opinion, food sensitivity testing is in a class of its own. It can demonstrate inflammatory processes in the gut as well as immune reactivity. When aiming to fix an irritable bowel, it’s important to understand that there are so many things that can be irritating it.

Food is the biggest irritator and since we eat food every day, it’s very important to address this to reduce inflammation.

Food sensitivity testing help to discover IBS

There are different tests for IBS, the food sensitivity testing in this lab in the US is one of the most recommended to measures your IgG reactivity levels.

Can You Test for Dysbiosis and The Microbiome?

You absolutely can, and uric acid (a key indicator of gout) is an excellent marker to use for dysbiosis or an unhealthy microbiome12. Uric acid is a good indicator of microbiome health because it shows improper metabolism of protein, typically due to unhealthy gut bugs.

Another my tests is the Organic Acids Test (OAT), which tracks overgrowth of yeasts as well as possible clostridium infections which aids in the support of patients with IBS.

There are also recent novel tests that will actually classify the types of healthy v.s. pathogenic microbes in your microbiome. This research is in its infancy.

What Should You Test? My Dream List

Here is my dream list, which is basically a full workup of a patient to rule out other sources of pain in the intestine:

  • CBC
  • Serum Electrolytes
  • Liver Enzymes, ALT, AST, ALP GGT
  • Urobilinogen, direct and indirect
  • Blood Lipids/Cholesterol
  • Albumin
  • eGFR and Creatinine
  • HS-CRP
  • Uric acid and urea
  • Iron panel including Ferritin
  • TSH, Free T3, Free T4, Antibodies for Thyroid
  • Dutch Hormone Test
  • Food Sensitivity Testing
  • OAT Test

What to Do While You’re Waiting to Get Your Tests Done? 

Start working on a solution!

My two first protocols for all patients is to start a Castor Oil Pack, which immediately begins to work on the stress component of their condition. It will reduce inflammation, help the body to cleanse, get the bowels moving and significantly reduce pain in the gut (I’ve used it more times than I can count for acute pain in my situation and it hasn’t failed). The Queen of the Thrones® Castor Oil Pack Bundle™ also helps you get a great night’s sleep.  

In addition, I encourage patients to wear an eye mask to bed. As mentioned before, this will help to increase the body’s natural melatonin production, improving quality of sleep. Get your Queen of the Thrones® Beauty Sleep Eye Kit™ to improve your sleep.

This is the basic start for all of my patients from the get go, because if we can start to reduce the stress, address the inflammation, cleanse, poop and sleep (these are common problems that every single person who walks into my practice shares) I can actually start getting a clearer picture of what is going on.

Peek After You Poo

The other pièce de résistance is that I ask my patients to start peeking at their poo. I want a detailed account moving forward. Because let’s face it, lab tests start to get quite expensive. For the full panel above you could be looking at anywhere between $1500-$2500 per shot, so why not learn what your poo is saying about you? It is an easy daily at-home test, totally free!
Use Queen of the Thrones® Eau De Throne™ the ‘After You Poo Parfum™’ to get into the habit of peeking after you poo and allow the blend of organic essential oils to ensure that you will never be embarrassed again for the smell you leave behind!

Learn about your gut health with Queen of The Thrones® 50 Shades of Poo Ebook

Every visit, with every single patient, we have this discussion and you would be shocked at how much it guides treatment. So much so, that I’ve compiled my personal experience, clinical experience and research so that you have access to the same tools as my patients. For a better understanding of what your poo says about you, download my free e-book ’50 Shades of Poo’

Start today! Don’t wait for tomorrow to do what you can do today. This is your health, your life, your body and it’s time for you to know and understand what is going on.

Don’t forget to share this with your friends on social media, through email and like us on Facebook, Instagram and YouTube to learn more about how you can OWN your throne!

References:

1 Bandar Mohammed Bardisi,1 Abdulaziz Kamal H. Halawani,1 Hassan Kamal H. Halawani,1 Aseel Hassan Alharbi,1 Nesma Saleh Turkostany,1 Taraji Saeed Alrehaili,1 Aisha Ahmad Radin,1 and Nasser Moqbil Alkhuzea1 Efficiency of diet change in irritable bowel syndrome. J Family Med Prim Care. 2018 Sep-Oct; 7(5): 946–951.PMID: 30598938

2 Emanuele Sinagra, Gaetano Cristian Morreale, Ghazaleh Mohammadian, Giorgio Fusco, Valentina Guarnotta, Giovanni Tomasello, Francesco Cappello, Francesca Rossi, Georgios Amvrosiadis, and Dario Raimondo New therapeutic perspectives in irritable bowel syndrome: Targeting low-grade inflammation, immuno-neuroendocrine axis, motility, secretion and beyond. World J Gastroenterol. 2017 Sep 28; 23(36): 6593–6627.PMID: 29085207

3 Ju Yup Lee and Kyung Sik Park. Gender Difference in Functional Gastrointestinal Disorders Korean J Gastroenterol. 2018 Oct 25;72(4):163-169. doi: 10.4166/kjg.2018.72.4.163.

4 Elizabeth J. Videlock,a Wendy Shih,b Mopelola Adeyemo,a Swapna Mahurkar-Joshi,a Angela P. Presson,c Christos Polytarchou,a Melissa Alberto,a Dimitrios Iliopoulos,a Emeran A. Mayer,a and Lin Changa,* The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression.Psychoneuroendocrinology. 2016 Jul; 69: 67–76.PMID: 27038676

5 Patacchioli FR1, Angelucci L, Dellerba G, Monnazzi P, Leri O. Actual stress, psychopathology and salivary cortisol levels in the irritable bowel syndrome (IBS). J Endocrinol Invest. 2001 Mar;24(3):173-7.

6 Robert L. Burr, MSEE, PhD, Research Professor,a Monica E. Jarrett, PhD, Professor,a Kevin C. Cain, PhD, Research Scientist,b Sang-Eun Jun, MS, Doctoral Candidate,a and Margaret M. Heitkemper, PhD, Professora. Catecholamine and Cortisol Levels during Sleep in Women with Irritable Bowel Syndrome.Neurogastroenterol Motil. 2009 Nov; 21(11): 1148–1e97.PMID: 19573081

7 Rong-fang Hu,1 Xiao-ying Jiang,1 Yi-ming Zeng,2 Xiao-yang Chen,2 and You-hua Zhang3 Effects of earplugs and eye masks on nocturnal sleep, melatonin and cortisol in a simulated intensive care unit environment. Crit Care. 2010; 14(2): R66.PMID: 20398302

8 Keren Hod, MSc,1,2 Tamar Ringel-Kulka, MD MPH,3 Christopher F. Martin, MSPH,2 Nitsan Maharshak, MD,4 and Yehuda Ringel, MD*,2 High Sensitive C – Reactive Protein as a Marker for Inflammation in Irritable Bowel Syndrome.J Clin Gastroenterol. 2016 Mar; 50(3): 227–232.PMID: 25930973

9 Tall AR1, Yvan-Charvet L2. Cholesterol, inflammation and innate immunity. Nat Rev Immunol. 2015 Feb;15(2):104-16. doi: 10.1038/nri3793.

10 Church MK1. Allergy, Histamine and Antihistamines. Handb Exp Pharmacol. 2017;241:321-331. doi: 10.1007/164_2016_85.

11 Wouters MM1, Van Wanrooy S1, Nguyen A2, Dooley J2, Aguilera-Lizarraga J1, Van Brabant W1, Garcia-Perez JE2, Van Oudenhove L1, Van Ranst M3, Verhaegen J4, Liston A2, Boeckxstaens G1 Psychological comorbidity increases the risk for postinfectious IBS partly by enhanced susceptibility to develop infectious gastroenteritis. Gut. 2016 Aug;65(8):1279-88. doi: 10.1136/gutjnl-2015-309460. Epub 2015 Jun 12.

12 Zhuang Guo,1,* Jiachao Zhang,1,* Zhanli Wang,3,* Kay Ying Ang,2,* Shi Huang,4 Qiangchuan Hou,1 Xiaoquan Su,4 Jianmin Qiao,1 Yi Zheng,1 Lifeng Wang,1 Eileen Koh,2 Ho Danliang,2 Jian Xu,4 Yuan Kun Lee,a,2 and Heping Zhangb,1 Intestinal Microbiota Distinguish Gout Patients from Healthy Humans Sci Rep. 2016; 6: 20602.PMID: 26852926 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757479/

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