Castor Oil Packs, Influenza (Flu), & Your Immune System

In 1918, the Spanish flu pandemic threatened the world population which was at about 1.8 billion people. 500 million people (about 1/3 of the population at the time) were infected. 

Mass graves had to be dug around the world as a result. Since then it seems we have been living in a state of fear and on high alert, for not IF but WHEN the next deadly mutated virus will hit again. 

The fear is even propagated and heightened because of our fixation; as evidenced in all the TV shows and movies about pandemics and zombie holocausts, like Outbreak with Dustin Hoffman, Contagion, and AMC’s The Walking Dead.  

Recent History

There have always been accounts of flu outbreaks. Remember SARS, the plagues of leprosy that stained faces, and those vanishing populations like the legendary Spanish flu of 1918?

The Spanish flu was the perfect example of what happens when a mutated virus meets malnourished, stressed, injured and inflamed soldiers, who jumped on boats at the end of the war to get home, and brought with them more than big hugs for their family – they brought the virus back to their homeland. 

These soldiers lived in less than sanitary conditions. Food options were limited to those that lined an aluminum can or those that were dried, requiring the simple addition of water (if you could find water, that is).

With limited hydration and good quality food the body suffers, plus add insult to injury of the severe mental stress that accompanies war-torn locations and PTSD, that many soldiers suffer from. I’m sure that not much can compare to living through that. Their physical bodies were wounded, inflamed and tossing and turning in their sleep. 

In essence, they were the perfect debilitate jalopy, the very best vehicle to propagate this deadly virus around the world. 

At home, many countries were ravaged by war, and once again, we see malnourished mothers and children who were stressed out and overworked. Trying to make ends meet and manage a household; the perfect receptacle to welcome the gift from their loved ones returning from war.

Likely to Get Sick | Conducive Conditions for Disease 

What conditions are ideal for diseases like influenza to flourish in? Think of it this way; our body is no different than a garden, or an ecosystem.

This is contrary to popular belief where many define the body as a machine. A machine can get pieces taken out of it. An ecosystem cannot; when one aspect is ripped out, it can be devastating to the entire system. 

There is one thing that is notorious for throwing off the beautiful balance in the ecosystem of our body. This one thing is STRESS, and in our bodies, this causes the “dis” in dis-ease. 

Here are a few of the many possible types of stress:

  • Digestive stress
  • Nutrient deficiency stress
  • Inflammatory and immune stress 
  • Mental and emotional stress 
  • Microbial stress

The list goes on and on…

We know that when we are weak and devitalized from repetitive, non-ceasing stress we are more prone to sickness. This is why influenza typically affects elderly populations, children and those with “dis-ease” or immune-compromised conditions more often. 

Notice the spelling of “dis-ease”.

The meaning of the prefix ‘dis’ is a body or system that is not in balance.

This is the same as a garden. One that lacks proper nutrients in the soil, adequate sunlight, water, or love messages won’t grow and is likely to develop infestations and disease. 

It only makes sense that the Spanish flu reached such staggering proportions and infected 1/3 of the world’s population at the time.

The true epidemic, in my opinion, may not have been one of the virus, but rather the overall state of health of the population of the world at the time. 

How about them apples? They should have been eating more!…

It was World War I, after all. Living in that time would mean constantly feeling an inner sensation of imbalance, that the ‘dis’ could come upon us at any time, and stress became programmed into the makeup of our bodies. Stress was the norm, not the exception as it should be.

Why We Focus On The Bug 

You may be familiar with Louis Pasteur, who in the 1800s popularized the idea of The Germ Theory and made it mainstream. The bug (virus, bacteria, yeast, parasite, etc), became the enemy to attack. Kill it and life is good. It was widely accepted as the main tenet that permeates medicine to this day; including in cancer treatments with the bug being our own tissues. 

But what most aren’t privy to, is that at the same time, Claude Bernard was promoting and proving the terrain theory, or physical vitalism. He postulated that the body is an ecosystem and that an ecosystem in health, has a vital force and can beat all disease1.

The difference, it was said, was that Pasteur had friends in high places that moved his philosophy forward. These have served us well, as we have learned an incredible amount about the bug and how it affects an unhealthy body. On the other hand, vitalism went backstage once Bernard was out of the picture. 

However, there is hearsay that Pasteur, on his deathbed, recanted his theory and said: “Bernard was right, it’s not about the bug, it’s the terrain”.

Why We Should Focus on Terrain, Vital Force, and Physical Vitalism of The Body

The ancient doctors of the past, Hippocrates, Galen, and Traditional Chinese Medicine Doctors always searched for ways to support the system as a whole. They focused on the foundation, the pillars that would create health. 

This is the mechanism of wellbeing, of positioning for success in spite of what is going on around you.

You really can’t control what is happening around you but one thing is for sure, you can control what you do. 

A healthy, well-balanced body with a solid foundation is in the right position to overcome anything that may come its way. This was the work that Bernard was so passionate about. 

If you have ever seen a naturopathic doctor, functional medicine doctor, or any other holistic healer, this is the premise of their work. 

A resilient, strong, balanced foundation in the body prevents all disease. 

The reality is that it’s about both the bug and the terrain, and keeping them in balance. 

Balance means we want a little bit of acute stress, not longterm constant stress as that becomes damaging, but a little goes a long way2, because it is actually protective, especially to the digestive tract and gut. 

As Hippocrates stated:

All disease begins in the gut

How to Prevent the Flu (From a Functional Perspective)

Our goal then is to support the foundation, which begins in the gut. To keep the body and its foundation well supported every day so that it can be healthy. 

Here I introduce to you The Original Cleanse. The formula used by the ancient doctors who knew the vital importance of making sure that a system can:

  • Poop well
  • Sleep well 
  • Cleanse well
  • Bloat less and digest well
  • Stress less and feel well

The simplest of functions and by far the most important is to feel better and be resilient against anything that comes its way.


The Original Cleanse is the combination of two ancient, powerful, time-honored practices; the castor oil pack and castor oil sleep mask routine.

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The Doctors of the Past

Doctors of the past lived by this adage:

The doctor dresses the wound and God [nature] heals it.3

As such, they would use the simplest of therapies such as a compress in the areas that needed help, in order to invigorate the vital force within to heal! Just like you do with a bandaid for a boo-boo.

Why do you think it’s so natural to simply put a bandage on it, or wrap it up? It is literally instinctual to us that it will help us heal. This is why they call it The Original Cleanse. It’s part of our origin story. It is that which will help us regain faith in our healing. 

The fact is wearing a compress, such as a castor oil pack, eye mask or bandage, stimulates the receptors of the skin that transfer information to the nervous system to put the body into the relaxed state. 

The skin provides the ‘on’ switch to the relaxed state by promoting the hormone oxytocin4, which reduces cortisol (the stress hormone). 

So the reason soldiers in World War I were so susceptible to the Spanish flu, was simply that wounds (whether an actual wound on the skin, emotional wound, or a misbalance in the immune system), don’t heal under stress5. It’s an impossibility. The system needs a calm, relaxed state that is flooded with oxytocin6 to heal. 

Wounds occur when the “equilibrium between synthesis and degradation has been shifted toward degradation”7.

The Natural Law of Balance 

The body follows a natural law of balance, otherwise, dis-ease predominates. The Original Cleanse works on setting up the foundation so there can be balance and no dis-ease. It is the simple practice of wearing a castor oil pack and eye mask with castor oil to bed every night.

My first experience with the castor oil pack was transformational, and later clinical experience with thousands of patients proved the same result. And it’s why I’m here telling everyone about them. 

For my patients and I, the first thing The Original Cleanse did was bring back FAITH in our ability to heal and feel better. It helped us to believe that balance could be achieved again, despite many failed attempts.

Very appropriately, I use the acronym FAITH to describe the five main foundations of health that castor oil packs support, which help to prepare it for any bug that comes its way. 

F: Function of the digestion, absorption, and elimination

Research demonstrates that castor oil enhances prostaglandins8, nitric oxide9 and stimulates capsaicin-sensitive sensory neurons10 in the presence of acute glucocorticoids (the hormones of stress), which actually has a protective effect on the gastric lining, thus improving its function.

Castor oil can enhance defensive mechanisms such as gastric acid as well as digestive enzymes, that serve as a barrier for bugs entering the body.

Castor oil packs have been shown to improve the frequency of elimination11, and via prostaglandin stimulation of smooth muscle and nitric oxide electrolyte shifting, reduces food sensitivities thus relieving the immune system. 

A: Antioxidant support 

Castor oil is a source of vitamin E, omega 6, omega 9, and the end result of what you get from fish oils12. It has also been shown to preserve levels of one of our most important antioxidants, glutathione13, which is required for detoxification in the liver. Wearing a castor oil pack over the liver supports circulation and flow to this area, allowing it to cleanse more efficiently.

I: Inflammation & Immunity

Inflammation must be reduced in the body to make space for healing. Castor oil is a strong anti-inflammatory14 and wearing a castor oil pack is an excellent way to reduce inflammation in the digestive tract. Castor oil packs have also been shown to support white blood cells of the immune system15 which protect our terrain from the bug. 

T: Tension/Stress

Stress is another key factor that must be reduced in order for healing to take place. Castor oil packs create a gentle compression that helps to move the body into the parasympathetic state16 and that stimulates feel-good hormones like dopamine17 and oxytocin18. Wearing a sleep mask helps to further support the reduction of stress by improving sleep via melatonin production19.

H: Host Microbial Balance

As mentioned earlier, the terrain is just as important as the bug. Part of the terrain of the body is the trillions of bugs (microscopic bacteria), known as the microbiome. A healthy balance of good bugs and bad bugs is a key player in the balance of our digestion, hormones and immune system function. Castor oil packs support the microbiome by helping to breakdown biofilm created by bad bugs20 21 22.

The Original Cleanse for Physical Vitalism

The Original Cleanse is a nightly practice that only takes 2 minutes, and helps to strengthen and balance the terrain of our bodies so that they are prepared for the bug, should it come-a-knockin’.  

Here’s how to do it:

Step 1: Prepare your castor oil pack by applying 1-2 tbsp of oil in the center of the soft cotton side of the pack, then tie it onto the body over the liver.

Step 2: Pour a dollop of castor oil into the palm of your hand. Use an applicator brush to apply castor oil to eyelashes and eyebrows, then dab the remaining oil into the delicate skin around the eyes. Cover with the eye mask and go to sleep. 

That’s it! The Original Cleanse revitalizes, strengthens and balances your body as you sleep.

Don’t forget to share this with your friends on social media, through email and to like us on Facebook, Instagram and YouTube to learn more about how to join the movement so that we can all have an improvement!

Disclaimer: Any opinions, advice, statements, services, offers, information or content expressed or made available by third parties, including information providers, are those of the respective authors or distributors. Neither Queen of the Thrones™ nor any third-party provider of information guarantees the accuracy, completeness, or usefulness of any content. This communication does not create a doctor-patient relationship. Information provided does not replace the advice of your health care practitioner. If you happen to purchase anything we promote, in this or any of our communications, it’s likely Queen of the Thrones™ will receive some kind of affiliate compensation. Still, we only promote content and products that we truly believe in and share with our friends, family and patients. If you ever have a concern with anything we share, please let us know at care@drmarisol.com. We want to make sure we are always serving Our Queendom at the highest level.


1 Normandin S1. Claude Bernard and an introduction to the study of experimental medicine: “physical vitalism,” dialectic, and epistemology. J Hist Med Allied Sci. 2007 Oct;62(4):495-528. Epub 2007 Jun 18. 

2 Filaretova LP.[Contribution of glucocorticoid hormones to gastroprotection]. Usp Fiziol Nauk. 2014 Jan-Mar;45(1):44-56.[Article in Russian]

3 https://irishwordsofwisdom.com/dr-joseph-murphys-prescription-for-self-healing/

4 Uvnas-Moberg K1, Petersson M.[Oxytocin, a mediator of anti-stress, well-being, social interaction, growth and healing]. Z Psychosom Med Psychother. 2005;51(1):57-80.[Article in German]

5 Vileikyte L1. Stress and wound healing. Clin Dermatol. 2007 Jan-Feb;25(1):49-55.

6 Detillion CE1, Craft TK, Glasper ER, Prendergast BJ, DeVries AC. Social facilitation of wound healing. Psychoneuroendocrinology. 2004 Sep;29(8):1004-11.

7 Menke NB1, Ward KR, Witten TM, Bonchev DG, Diegelmann RF. Impaired wound healing.Clin Dermatol. 2007 Jan-Feb;25(1):19-25.

8   Sorin Tunaru,a Till F. Althoff,a Rolf M. Nüsing,b Martin Diener,c and Stefan Offermannsa,d,1 Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors. Proc Natl Acad Sci U S A. 2012 Jun 5; 109(23): 9179–9184. Published online 2012 May 21. doi: 10.1073/pnas.1201627109 PMID: 22615395

9   Mascolo N1, Izzo AAAutore GBarbato FCapasso F.Nitric oxide and castor oil-induced diarrhea.J Pharmacol Exp Ther. 1994 Jan;268(1):291-5.

10  Vieira C et al. .Effect of ricinoleic acid in acute and subchronic experimental models of inflammation. Mediators Inflamm. 2000;9(5):223-8

11   Arslan GG, Eşer I. An examination of the effect of castor oil packs on constipation in the elderly. Complement Ther Clin Pract. 2011 Feb;17(1):58-62. doi: 10.1016/j.ctcp.2010.04.004. Epub 2010 May 18.

12  Marwat SK, Rehman F, Khan EA, Baloch MS, Sadiq M, Ullah I, Javaria S, Shaheen S. Review – Ricinus cmmunis – Ethnomedicinal uses and pharmacological activities.Pak J Pharm Sci. 2017 Sep;30(5):1815-1827.

13   Holm TBrøgger-Jensen MRJohnson LKessel L.Glutathione preservation during storage of rat lenses in optisol-GS and castor oil. PLoS One. 2013 Nov 19;8(11):e79620. doi: 10.1371/journal.pone.0079620. eCollection 2013.

14  Vieira C et al. .Effect of ricinoleic acid in acute and subchronic experimental models of inflammation. Mediators Inflamm. 2000;9(5):223-8

15  Grady H. Immunomodulation through castor oil packs. The Journal of Naturopathic Medicine. Volume 7 Jan 1 1998; 7(1): 84-9

16  Löken LS, Wessberg J, Morrison I, McGlone F, Olausson H. Coding of pleasant touch by unmyelinated afferents in humans. Nat Neurosci. 2009 May;12(5):547-8. Epub 2009 Apr 12

17   Rolls ET et all. Representations of pleasant and painful touch in the human orbitofrontal and cingulate cortices. Cereb Cortex. 2003 Mar;13(3):308-17.

18   Walker SC1, Trotter PD2, Swaney WT2, Marshall A3, Mcglone FP4. C-tactile afferents: Cutaneous mediators of oxytocin release during affiliative tactile interactions? Neuropeptides. 2017 Aug;64:27-38. doi: 10.1016/j.npep.2017.01.001. Epub 2017 Jan 19.

19  Rong-fang HuXiao-ying JiangYi-ming ZengXiao-yang ChenYou-hua Zhang. Effects of earplugs and eye masks on nocturnal sleep, melatonin and cortisol in a simulated intensive care unit environment. Published online 2010 Apr 18. doi: 10.1186/cc8965

20   Andrade IM1, Andrade KM2, Pisani MX1, Silva-Lovato CH1, de Souza RF1, Paranhos Hde F1.Trial of an experimental castor oil solution for cleaning dentures. Braz Dent J. 2014 Jan-Feb;25(1):43-7.

21   Badaró MM, Salles MM, Leite VMF, Arruda CNF, Oliveira VC, Nascimento CD, Souza RF, Paranhos HFO, Silva-Lovato CH. Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser.J Appl Oral Sci. 2017 May-Jun; 25(3):324-334.

22   Salles MM, Badaró MM, Arruda CN, Leite VM, Silva CH, Watanabe E, Oliveira Vde C, Paranhos Hde F. Antimicrobial activity of complete denture cleanser solutions based on sodium hypochlorite and Ricinus communis – a randomized clinical study.J Appl Oral Sci. 2015 Nov-Dec; 23(6):637-42.

Irritable Bowel Syndrome and the Microbiome | Part 2 | Dr. Marisol

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Last week in my blog post,  Irritable Bowel Syndrome and the Microbiome | Part 1, we learned about the theories of Pasteur and Bernard, germ theory vs. terrain theory. And, contrary to popular belief in western medicine, it seems that the terrain is the most important aspect when managing the bug.

Probiotic Supplements – Do they Make Sense?

Let me put it in two clear examples for you. You’re told to take probiotics. One pill a day that has 50 billion bacteria. Does it really make sense that this is going to compensate for the 100 trillion bacteria that you have in your intestine? One pill. Wow, must be some kind of magical mystical pill.

What happens when you stop taking it or change your diet or lifestyle? You’re going to have to take way more probiotics if your lifestyle and environment becomes sicker, or way less if your lifestyle and environment becomes healthier. Capiche? Do you see why addressing the body as a whole makes way more sense?

Fecal Transplants – Do they Make Sense?

What about the big buzz word these days, fecal transplants. They are probably more of a buzz because of their inherent shock factor.

They make sense for the moment if you’re willing to be a candidate to put someone else’s poo into your body. In lab studies, transplanting an IBS patient’s stools into healthy mice actually gave the mice unhealthy metabolic profiles, different from the healthy stools1.

However, I caution… again, you can transplant the stools, but if your lifestyle and environment, your millieu changes, due to stress or the other factors, what happens is your microbiome will change too. Back to the beginning, no further ahead, only a little bit more full of shit (LOL!).

It’s so simple it hurts my head. I hope it’s hurting yours (not because I want to inflict pain, but I want your eyes to open!)

IBS as a Functional Disorder

In addition to all of this, irritable bowel syndrome is a FUNCTIONAL disturbance of the digestive tract. Does it not then beg for treatment that is functional in form, hence a SYSTEMS biology approach, and not one that reduces it down simply to the microbiome2?

The point of this whole blog is this….

IT’S ABOUT LOOKING AT THE BIG AND THE SMALL, SIMULTANEOUSLY.

Because this is the natural logic in our living system. Some systems are grand and complex, like our hormonal regulatory system, and others are less complex and small, like a bacterium. But the reality is that because they all exist together, they must all work together.

The issue for Bernard was that his workings appreciated that we lived as a whole of our systems, and that physiological phenomena always seemed to find balance with highly defined set points. So now I’m encouraging you to think of the whole and not the parts in isolation when you’re considering what to do about your irritable bowel.

What would a systems/whole approach entail?

1. Get the Junk Out – Don’t Let It Pile Up

Terrain is, in effect, how we keep our bodies clean from the waste that perturbs its natural function. Think of it like this. If you kept the garbage piling up in your house, instead of packaging it and taking it to the curb, eventually you wouldn’t be able to get into your house to do the things that you need to. The body is no different. Whether the garbage comes from the byproducts of the microbiome, your own metabolism or the food that you eat, at the end of the day it’s all garbage.

Another analogy that I just love is thinking of the fish tank. A fish, in essence, swims in its own filth unless you clean out the tank. Think of the fish like one of your cells. It spits out, pisses and poops out what it doesn’t need into the water. If your body, or the fish tank, is never cleaned, you get scum build up. The scum that makes the glass cloudy and eventually makes it difficult for the fish, a.k.a. the cell, to survive. This is a good way to understand “le millieu liquide” as Bernard understood it.

The focus has shifted from keeping up on housekeeping rather than having a war on the virus. The premise is a strong system that is free of debris. Its “vital force” is intact and it is able to keep the balance between the good and the bad3.

2. Nurture It Like you Would a Garden

I look at it as if our body is a garden. We must feed it, give it water and light, sing to it, make it joyous, reduce the stress, try to avoid natural disasters and natural prey.

As any farmer will tell you, and I have had this conversation with many of my patients that are farmers… “You reap what you sow. If you put in good, you get out good, and more importantly, good takes time.”

We are not looking at dropping a nuke and killing off all the bugs, rather we are willing to put in the time day to day, to get good results. Farmers very much resonate with natural medicine and systems biology because they live it on a daily basis in their work, so it’s so very easy to extend it into their lives.

Our #1 Product to Help with Understanding what our Body is Saying

To help you figure out what the problem is, you fortunately have something very close at your disposable, a totally free assessment. Your stools are one of the best ways to understand what is going on inside your body.

Poop is classically known in our language as #2, but I firmly believe that it was mislabeled and should be called #1, as it is the most important product we produce. It gives us real-time knowledge about what is going on in our bodies. As long as we learn to poop, peek and then assess, we’ve got it all covered. 

Our stools are the window into our digestion, absorption, and elimination. They show vitamin and mineral deficiencies, hormonal, immune, and nervous system problems. They suggest inflammation, food sensitivities, excess mucus in the body. They are basically the owner’s manual to your health… If you know how to read them. 

Dr. Marisol - Digestive Detective

Poo comes in all shapes and forms and sizes, and that is exactly how we like it because that’s how it is used as a guide to your body’s health. Whether it’s a cow plop or an Oktoberfest sausage… whether it sinks or floats… whether or not it smells like rotten eggs… They’re all key indications to the state of our health. Click here to grab your complimentary check list and to find out what the colour of your poo says about you!

Environments Have Timing, So Does your Poo

Another majorly important factor is timing. All systems have timing. With your stools, it’s incredibly important for them to work well and for you to track how often and when you go. The ideal is a 24-hour cycle. A longer stool timing is linked to increased allergy and food sensitivity4, as one example, but there is much more it is linked to.

Timing is everything. Even your microbiome is doing different things depending on the clues in your environment5, following the day and night cycle, or circadian rhythm. So it makes sense that when you’re working on your systems, or your terrain, to start with the most important cycle to optimize.

Change your Terrain – Fix your Irritable Bowel

So now, what are you thinking? Do you still want to target the microbiome? I doubt it! I think now you understand that you must fix the environment and the rest will follow (there are a few exceptions to this rule, so always make sure that you check with your health care provider for what is right for you).

Night Practice for Irritable Bowel Terrain Treatment

My most important medicines for the terrain are the oldest therapies of them all. Likely because they had their roots long ago when people were in tune with these vitalistic principles.

Nightly Restorative Sleep Practice

Sleep is the most important part of our day. So like I do with all of my patients, we start here. We do the majority of our house-work while we’re sleeping, unbeknownst to you… As long as you get a deep and regenerative sleep. Even the microbiome potentially follows the natural day and night cycles6!

If you were like me, when I was in the stormy season of my irritable bowel, I couldn’t sleep for the life of me. Because of this, I was a mess emotionally and my WHOLE life felt like a mess, a hot mess. One of the top complaints made by irritable bowel syndrome sufferers is fatigue. And this is no surprise because if your body is confused with its hormones, nutrient deficiencies and microbiome mayhem, how can you get a good night sleep?

These are the most important tips:

  • Cool your room 
  • Complete darkness
  • Your bed is for sex and sleep only – try having sex before sleep that’ll help you doze off into never, never land
  • Don’t eat for at least 2 hours before bed 
  • Avoid caffeinated beverages past 3 pm (coffee, tea, green tea, pop, energy drinks) 
  • Alcohol – don’t over do it, it’ll wake you 
  • Create a routine every night, the same thing 
  • Journal for one page, write down what you need to do tomorrow and 3 things that you are grateful for 
  • Wear an eye mask like the one in the Beauty Sleep Eye Kit – this helps to naturally promote melatonin7 which does wonders for your sleep! 
  • Use your castor oil pack!

Castor Oil Packs – A Legendary Terrain Treatment

Castor oil packs deserve special mention. So many of us go to bed stressed out and worried about the next day. So we tumble, toss and turn, and do nothing but hyper worry about the day we just had and what’s to come.

When you place a castor oil pack on your body it immediately switches your system into the relaxed state. Ah, zen time for me. So you can sleep and heal and reap the benefits. Click here to get the Queen of the Thrones™ Castor Oil Pack Pack and 500ml Castor Oil Bundle!

On top of it, there are so many wonderful actions of the pack that help your body to do the clean up during the night. They help to:

  1. Reduce inflammation and improve the alkalinity of your body8 9
  2. Enhance antioxidants like glutathione that help your body to cleanse10
  3. Move the bowels – typically the next morning you’re happy to let go of a load!11 12 
  4. Breakdown biofilm – a barrier created by the bad bugs of the microbiome. Getting rid of this gunk allows you to heal your gut 13 14
  5. Don’t forget they help you to relax15 16 so you can sleep!

Your sleep will be regenerative, healthy, fulfilling, and satisfying. You’ll be ready to take on your day. Most importantly, you will have done the important step of helping to reset your terrain while you sleep. 

NEXT STEPS

My hope is that you start by looking at what your poo is saying about you and that you begin to address the ever-important sleep function of your body. I love the saying, “cleanliness is next to godliness”, and starting these practices are the very first steps to getting your body in a better, healthier, and cleaner state. 

Don’t forget to share this with your friends on social media, through email and to like us on Facebook, Instagram and YouTube to learn more about joining the movement so that we can all have an improvement!

Disclaimer: Any opinions, advice, statements, services, offers, information or content expressed or made available by third parties, including information providers, are those of the respective authors or distributors. Neither Queen of the Thrones™ nor any third-party provider of information guarantees the accuracy, completeness, or usefulness of any content. This communication does not create a doctor-patient relationship. Information provided does not replace the advice of your health care practitioner. If you happen to purchase anything we promote, in this or any of our communications, it’s likely Queen of the Thrones™ will receive some kind of affiliate compensation. Still, we only promote content and products that we truly believe in and share with our friends, family and patients. If you ever have a concern with anything we share, please let us know at care@drmarisol.com. We want to make sure we are always serving Our Queendom at the highest level.

References:
1 De Palma G1, Lynch MD2, Lu J1, Dang VT3, Deng Y1, Jury J1, Umeh G1, Miranda PM1, Pigrau Pastor M1, Sidani S1, Pinto-Sanchez MI1, Philip V1, McLean PG4, Hagelsieb MG5, Surette MG1, Bergonzelli GE4, Verdu EF1, Britz-McKibbin P3, Neufeld JD2, Collins SM1, Bercik P6. Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice. Sci Transl Med. 2017 Mar 1;9(379). pii: eaaf6397. doi: 10.1126/scitranslmed.aaf6397.

2 Şimşek I1. Irritable bowel syndrome and other functional gastrointestinal disorders. J Clin Gastroenterol. 2011 Aug;45 Suppl:S86-8. doi: 10.1097/MCG.0b013e31821fbd6f.

3 Normandin S1. Claude Bernard and an introduction to the study of experimental medicine: “physical vitalism,” dialectic, and epistemology.  J Hist Med Allied Sci. 2007 Oct;62(4):495-528. Epub 2007 Jun 18.

4 Pali-Schöll I1,2, Untersmayr E3, Klems M4, Jensen-Jarolim E5,6. The Effect of Digestion and Digestibility on Allergenicity of Food. Nutrients. 2018 Aug 21;10(9). pii: E1129. doi: 10.3390/nu10091129.

5 Nobs SP1, Tuganbaev T1, Elinav E2,3. Microbiome diurnal rhythmicity and its impact on host physiology and disease risk.EMBO Rep. 2019 Mar 15. pii: e47129. doi: 10.15252/embr.201847129. [Epub ahead of print]

6 Liang X1, FitzGerald GA2. Timing the Microbes: The Circadian Rhythm of the Gut Microbiome. J Biol Rhythms. 2017 Dec;32(6):505-515. doi: 10.1177/0748730417729066. Epub 2017 Sep 1.

7 Hu RF1, Jiang XY, Chen J, Zeng Z, Chen XY, Li Y, Huining X, Evans DJ. Non-pharmacological interventions for sleep promotion in the intensive care unit. Cochrane Database Syst Rev. 2015 Oct 6;(10):CD008808. doi: 10.1002/14651858.CD008808.pub2.

8 Vieira C et al. .Effect of ricinoleic acid in acute and subchronic experimental models of inflammation. Mediators Inflamm. 2000;9(5):223-8.

9  Grady H. Immunomodulation through castor oil packs. The Journal of Naturopathic Medicine. Volume 7 Jan 1 1998; 7(1): 84-9

10  Holm T1, Brøgger-Jensen MR, Johnson L, Kessel L. Glutathione preservation during storage of rat lenses in optisol-GS and castor oil. PLoS One. 2013 Nov 19;8(11):e79620. doi: 10.1371/journal.pone.0079620. eCollection 2013.

11  Arslan GG, Eşer I. An examination of the effect of castor oil packs on constipation in the elderly. Complement Ther Clin Pract. 2011 Feb;17(1):58-62. doi: 10.1016/j.ctcp.2010.04.004. Epub 2010 May 18.

12  Sorin Tunaru,a Till F. Althoff,a Rolf M. Nüsing,b Martin Diener,c and Stefan Offermannsa,d,1 Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptorsProc Natl Acad Sci U S A. 2012 Jun 5; 109(23): 9179–9184.Published online 2012 May 21. doi: 10.1073/pnas.1201627109PMID: 22615395

13  Andrade IM1, Andrade KM2, Pisani MX1, Silva-Lovato CH1, de Souza RF1, Paranhos Hde F1. Trial of an experimental castor oil solution for cleaning dentures. Braz Dent J. 2014 Jan-Feb;25(1):43-7.

14  Badaró MM, Salles MM, Leite VMF, Arruda CNF, Oliveira VC, Nascimento CD, Souza RF, Paranhos HFO, Silva-Lovato CH. Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser.J Appl Oral Sci. 2017 May-Jun; 25(3):324-334.

15  Walker SC1, Trotter PD2, Swaney WT2, Marshall A3, Mcglone FP4. C-tactile afferents: Cutaneous mediators of oxytocin release during affiliative tactile interactions? Neuropeptides. 2017 Aug;64:27-38. doi: 10.1016/j.npep.2017.01.001. Epub 2017 Jan 19.

16  Rolls ET et all. Representations of pleasant and painful touch in the human orbitofrontal and cingulate cortices. Cereb Cortex. 2003 Mar;13(3):308-17. ( Dopamine release, Limbic System of brain- Fatty Meal Satisfaction) 

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Best Lab Tests to Help Treat Your Irritable Bowel Syndrome

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So you’ve been diagnosed with irritable bowel syndrome (IBS). Now what?? As someone who has IBS, I’ve experienced first hand how debilitating it can be, and how confusing the diagnostic process is. I want to share with you some things that I wish I would have known back when I got my diagnosis, that would have saved me years of excruciating pain and suffering. I have now seen thousands of patients who also have this diagnosis live a legendary life.

Why is Irritable Bowel Syndrome a Functional Bowel Movement Disorder?

Irritable bowel syndrome is classified as a chronic functional bowel movement disorder because it is diagnosed by the symptoms that you are experiencing. These are typically abdominal pain, gas, bloating, and changes in bowel movements, often diarrhea or constipation1. Other digestive diseases that can be seen by colonoscopy or confirmed by lab tests are often excluded before IBS is diagnosed.

Why Can’t Labs Tell Me That I Have Irritable Bowel Syndrome?

The labs that most conventional doctors use at this moment in time don’t give a definitive diagnosis of irritable bowel syndrome. This is because it is a complex interplay of all the processes in our body. It is most often a reaction to stress in the body, whether emotional or physical, that creates an imbalance in the immune, nervous and hormonal systems. This compounds and affects the natural digestive processes of the gut, causing inflammation, irritation, dysbiosis and lack of digestive factors that all contribute to and aggravate our symptoms2.

The big point here is that it is NOT just one thing causing IBS, and to treat it you need to have a MULTIFACTORIAL approach or it just won’t work.

Functional Disorders Involve the ENTIRE Environment of the Body 

As a Naturopathic Doctor, we look at the body as a complete environment, an ecosystem. I have expertise in digestive disorders, specifically irritable bowel syndrome. I am also extremely well versed in hormonal problems such as hypothyroid, estrogen dominance, nervous system conditions like anxiety and depression, and immune system problems like Hashimoto’s thyroiditis, celiac disease, cancer, Crohn’s, ulcerative colitis and I have treated all successfully.

If I only knew about the gut and digestive system, I wouldn’t be able to treat a FUNCTIONAL digestive system disorder because functional means that the whole entire body is involved. The ecosystem needs rebalancing.

Are There Functional Tests for Irritable Bowel Syndrome?

Yes, there are things that can be tested, but again, it is a whole body approach. So as a Naturopathic Doctor I can see that there are imbalances in the whole body.

What Is the Point of Testing in Irritable Bowel Syndrome?

First off, it’s important to do tests to rule out other conditions. When the diagnosis is clear, I test irritable bowel patients in order to track improvements and direct and guide treatment.

For my health as well, I have noticed that it is vital to have this tracking system over time in order to gain a good understanding of what is going on inside your system, year to year.

Since irritable bowel is a chronic, long term disease, being proactive in this way helps to stay on top of things and avoid the frustration and suffering of living with uncomfortable symptoms.

Stress Hormone Testing Cortisol and ACTH 

Research demonstrates that people with irritable bowel syndrome, mainly women, with onset at a younger age3, will have it for the greater part of their lives. They typically also have an imbalance in their nervous system and stress response.

Stress markers of cortisol in the blood can be tested and show a difference between men and women as well as between healthy and unhealthy subjects4. However, this is a costly test and is not common protocol for irritable bowel syndrome.

Salivary or urine cortisol markers can also be used to measure this, and they are my markers of choice. Research demonstrates that there is a significant difference in cortisol (stress hormone) markers in the morning and evening, and in general there was a higher spike in the a.m. and lower in the evening. The pattern of circadian rhythm night and day curve was still maintained5.

These tests can be purchased on YourLabWork.com.

Sleep is often something that is a complaint for women with IBS and there seems to be a difference between the type, whether it be IBS-D (diarrhea predominant) or IBS-C (constipation predominant)6. Sleep is something that normally balances our regulatory systems as it helps to reset the immune, nervous and hormonal systems.

I recommend wearing an eye mask to bed at night to help support natural melatonin production, without having to take a supplement. I’ve created a Beauty Sleep Kit that uses castor oil applied around the eyes, eyelashes and eyebrows, covered by a sleep mask. This has a relaxing effect on the system and improves natural melatonin levels, helping you to get a good night’s sleep. You will note over time, visible differences in sleep quality with using a mask7.

GET YOUR BEAUTY SLEEP KIT HERE!

Inflammation Testing in IBS 

Inflammation is a key component in IBS. Inflammation may be sourced from food sensitivities, allergies and intolerances, or choices of food, such as fermented foods that have high levels of histamine and act as an irritant to the gut. Inflammation is a root cause of all diseases and when there is imbalance in any system there is always inflammation.

Ferritin, the storage molecule for iron can also be a key indicator of acute inflammation. It is important to test in combination with a complete blood count (CBC) as well as an iron panel to make sure you rule out any other reasons for an elevated level of Ferritin.

In my practice there are certain key markers that I have noted are indicative inflammation. Firstly, high sensitivity C reactive protein (HS-CRP). This marker is not often tested, however, levels have been noted to be higher in those with irritable bowel syndrome as compared to the healthy population8.

Cholesterol has also been one of the markers of inflammation that I use to track progress in patients. It is linked to inflammatory processes in the body and I have seen clear indications post therapeutic cleansing interventions with my patients, where even if cholesterol is only moderately higher, it always decreases from the pre-testing phase9. I always test these levels in my IBS patients because I want to see how they are adapting to their protocols and where they are at the present state in time.

A complete blood count (CBC) is always important to do as well, because it demonstrates a variety of markers. With regards to inflammation, eosinophils are a marker of allergy and when they are elevated it’s an indicator that there is elevated histamines in the body10. It’s most commonly correlated to parasite infection, which is something to be considered in irritable bowel syndrome, since the onset of IBS can be due to a gastrointestinal infection11.

In my opinion, food sensitivity testing is in a class of its own. It can demonstrate inflammatory processes in the gut as well as immune reactivity. When aiming to fix an irritable bowel, it’s important to understand that there are so many things that can be irritating it.

Food is the biggest irritator and since we eat food every day, it’s very important to address this to reduce inflammation.

This website has more information on food sensitivity testing in the US.

Can You Test for Dysbiosis and The Microbiome?

You absolutely can, and uric acid (a key indicator of gout) is an excellent marker to use for dysbiosis or an unhealthy microbiome12. Uric acid is a good indicator of microbiome health because it shows improper metabolism of protein, typically due to unhealthy gut bugs.

Another my tests is the Organic Acids Test (OAT), which tracks overgrowth of yeasts as well as possible clostridium infections which aids in the support of patients with IBS.

There are also recent novel tests that will actually classify the types of healthy v.s. pathogenic microbes in your microbiome. This research is in its infancy.

What Should You Test? My Dream List

Here is my dream list, which is basically a full workup of a patient to rule out other sources of pain in the intestine:

  • CBC
  • Serum Electrolytes
  • Liver Enzymes, ALT, AST, ALP GGT
  • Urobilinogen, direct and indirect
  • Blood Lipids/Cholesterol
  • Albumin
  • eGFR and Creatinine
  • HS-CRP
  • Uric acid and urea
  • Iron panel including Ferritin
  • TSH, Free T3, Free T4, Antibodies for Thyroid
  • Dutch Hormone Test
  • Food Sensitivity Testing
  • OAT Test

What to Do While You’re Waiting to Get Your Tests Done? 

Start working on a solution!

My two first protocols for all patients is to start a castor oil pack, which immediately begins to work on the stress component of their condition. It will reduce inflammation, help the body to cleanse, get the bowels moving and significantly reduce pain in the gut (I’ve used it more times than I can count for acute pain in my situation and it hasn’t failed). It will also help you get a great night’s sleep. The Queen of the Thrones™ Castor Oil Pack Bundle™ is available here

In addition, I encourage patients to wear an eye mask to bed. As mentioned before, this will help to increase the body’s natural melatonin production, improving quality of sleep. The Queen of the Thrones™ Beauty Sleep Eye Kit™ is available here

This is the basic start for all of my patients from the get go, because if we can start to reduce the stress, address the inflammation, cleanse, poop and sleep (these are common problems that every single person who walks into my practice shares) I can actually start getting a clearer picture of what is going on.

Peek After You Poo

The other pièce de résistance is that I ask my patients to start peeking at their poo. I want a detailed account moving forward. Because let’s face it, lab tests start to get quite expensive. For the full panel above you could be looking at anywhere between $1500-$2500 per shot, so why not learn what your poo is saying about you? It is an easy daily at-home test, totally free!
Use Eau De Throne™ the ‘After You Poo Parfum™’ to get into the habit of peeking after you poo and allow the blend of organic essential oils to ensure that you will never be embarrassed again for the smell you leave behind!

Every visit, with every single patient, we have this discussion and you would be shocked at how much it guides treatment. So much so, that I’ve compiled my personal experience, clinical experience and research so that you have access to the same tools as my patients. For a better understanding of what your poo says about you, download my free e-book ’50 Shades of Poo’ here

 

Start today! Don’t wait for tomorrow to do what you can do today. This is your health, your life, your body and it’s time for you to know and understand what is going on.

Don’t forget to share this with your friends on social media, through email and like us on Facebook, Instagram and YouTube to learn more about how you can OWN your throne!

References:

1 Bandar Mohammed Bardisi,1 Abdulaziz Kamal H. Halawani,1 Hassan Kamal H. Halawani,1 Aseel Hassan Alharbi,1 Nesma Saleh Turkostany,1 Taraji Saeed Alrehaili,1 Aisha Ahmad Radin,1 and Nasser Moqbil Alkhuzea1 Efficiency of diet change in irritable bowel syndrome. J Family Med Prim Care. 2018 Sep-Oct; 7(5): 946–951.PMID: 30598938

2 Emanuele Sinagra, Gaetano Cristian Morreale, Ghazaleh Mohammadian, Giorgio Fusco, Valentina Guarnotta, Giovanni Tomasello, Francesco Cappello, Francesca Rossi, Georgios Amvrosiadis, and Dario Raimondo New therapeutic perspectives in irritable bowel syndrome: Targeting low-grade inflammation, immuno-neuroendocrine axis, motility, secretion and beyond. World J Gastroenterol. 2017 Sep 28; 23(36): 6593–6627.PMID: 29085207

3 Ju Yup Lee and Kyung Sik Park. Gender Difference in Functional Gastrointestinal Disorders Korean J Gastroenterol. 2018 Oct 25;72(4):163-169. doi: 10.4166/kjg.2018.72.4.163.

4 Elizabeth J. Videlock,a Wendy Shih,b Mopelola Adeyemo,a Swapna Mahurkar-Joshi,a Angela P. Presson,c Christos Polytarchou,a Melissa Alberto,a Dimitrios Iliopoulos,a Emeran A. Mayer,a and Lin Changa,* The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression.Psychoneuroendocrinology. 2016 Jul; 69: 67–76.PMID: 27038676

5 Patacchioli FR1, Angelucci L, Dellerba G, Monnazzi P, Leri O. Actual stress, psychopathology and salivary cortisol levels in the irritable bowel syndrome (IBS). J Endocrinol Invest. 2001 Mar;24(3):173-7.

6 Robert L. Burr, MSEE, PhD, Research Professor,a Monica E. Jarrett, PhD, Professor,a Kevin C. Cain, PhD, Research Scientist,b Sang-Eun Jun, MS, Doctoral Candidate,a and Margaret M. Heitkemper, PhD, Professora. Catecholamine and Cortisol Levels during Sleep in Women with Irritable Bowel Syndrome.Neurogastroenterol Motil. 2009 Nov; 21(11): 1148–1e97.PMID: 19573081

7 Rong-fang Hu,1 Xiao-ying Jiang,1 Yi-ming Zeng,2 Xiao-yang Chen,2 and You-hua Zhang3 Effects of earplugs and eye masks on nocturnal sleep, melatonin and cortisol in a simulated intensive care unit environment. Crit Care. 2010; 14(2): R66.PMID: 20398302

8 Keren Hod, MSc,1,2 Tamar Ringel-Kulka, MD MPH,3 Christopher F. Martin, MSPH,2 Nitsan Maharshak, MD,4 and Yehuda Ringel, MD*,2 High Sensitive C – Reactive Protein as a Marker for Inflammation in Irritable Bowel Syndrome.J Clin Gastroenterol. 2016 Mar; 50(3): 227–232.PMID: 25930973

9 Tall AR1, Yvan-Charvet L2. Cholesterol, inflammation and innate immunity. Nat Rev Immunol. 2015 Feb;15(2):104-16. doi: 10.1038/nri3793.

10 Church MK1. Allergy, Histamine and Antihistamines. Handb Exp Pharmacol. 2017;241:321-331. doi: 10.1007/164_2016_85.

11 Wouters MM1, Van Wanrooy S1, Nguyen A2, Dooley J2, Aguilera-Lizarraga J1, Van Brabant W1, Garcia-Perez JE2, Van Oudenhove L1, Van Ranst M3, Verhaegen J4, Liston A2, Boeckxstaens G1 Psychological comorbidity increases the risk for postinfectious IBS partly by enhanced susceptibility to develop infectious gastroenteritis. Gut. 2016 Aug;65(8):1279-88. doi: 10.1136/gutjnl-2015-309460. Epub 2015 Jun 12.

12 Zhuang Guo,1,* Jiachao Zhang,1,* Zhanli Wang,3,* Kay Ying Ang,2,* Shi Huang,4 Qiangchuan Hou,1 Xiaoquan Su,4 Jianmin Qiao,1 Yi Zheng,1 Lifeng Wang,1 Eileen Koh,2 Ho Danliang,2 Jian Xu,4 Yuan Kun Lee,a,2 and Heping Zhangb,1 Intestinal Microbiota Distinguish Gout Patients from Healthy Humans Sci Rep. 2016; 6: 20602.PMID: 26852926 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757479/

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